Syncom has successfully carried out numerous carbohydrate synthesis contract research projects for a variety of companies. Among our clients we count leading companies in the pharmaceutical and biotechnology industries, as well as ambitious start-ups from various industries. Our chemists are experienced and talented with all the required skills for the successful completion of carbohydrate projects. As such, we consider carbohydrate synthesis.
Custom carbohydrate synthesis at Syncom
The involvement of carbohydrates in numerous medically relevant processes has stimulated the development of carbohydrate metabolites and synthetic carbohydrates for toxicity studies, drug delivery, and therapeutic investigations. Syncom has performed carbohydrate synthesis on several complex oligosaccharides, often on a 10g – 100g scale. Through manipulation of functional and protecting groups of monosaccharides, Syncom has performed specific coupling reactions and derivatizations. Additionally, we have developed diverse multi-step synthetic routes to novel carbohydrates to provide complex di, ti-, and even pentasaccharides.
Furthermore, our chemists have prepared various glucuronide metabolites of pharmaceuticals. We have a stock of reactive intermediates which enable fast synthesis of glucuronides, glucuronide carbamates, quaternary N-glucuronide salts and 1-0 acyl glucuronides. We also prepared azasugars such as 1-deoxynojirimycin and various derivatives thereof on both large and small scale. Are you looking for stable isotope labeled derivatives? We have the ability to prepare those for you as well.